Figure 4.
Adoptive transfer. (A) Blood mononuclear cells (1 × 107) were harvested from donor mice treated with G-CSF and AMD3100 and infused intravenously into recipient mice 24, 48, and 72 hours after induction of hindlimb ischemia. Blood flow was measured by laser Doppler perfusion imaging. (B) Capillary density of adductor muscle from ischemic hindlimbs at day 14 after surgery (*P = .001). (C) Mobilized or nonmobilized blood mononuclear cells (5 × 106) were infused intravenously 24 hours after induction of hindlimb ischemia. The difference between mice receiving mobilized or nonmobilized cells was not significant (P = .71). Data represent the mean ± SEM.