Figure 2.
The repertoire of clonal HSC repopulation kinetics. Each graph depicts a different family of repopulation kinetics, identified after comparison of symbolized kinetics by Hamming distance. The symbolized slopes for each group of kinetics are indicated in each panel, where the slope of each segment is expressed as positive (+), negative (–), or flat (π). Groups were further subdivided according to whether their AUC value was high (↑) or low (↓). Solid lines indicate data from the same 57 mice shown in Figure 1A. The dashed lines portray similarly analyzed data from 27 HSC clones followed in mice that received injections of freshly isolated BM cells (in vivo LD).