Relationship of serum LDH levels and history of vasculopathic complications. (A) The frequency distribution of 213 patients with sickle cell disease by LDH level in hundreds is indicated by the vertical bars. For comparison of the prevalence of selected sickle cell complications, data from 213 patients are divided into 3 groups according to serum LDH levels. The low LDH is defined by LDH levels lower than 1 SD below the overall mean (range, 121-189 IU/L), medium LDH by overall mean LDH level plus or minus 1 SD (range, 190-511 IU/L), and high LDH higher than 1 SD above the overall mean (range, 512-1171 IU/L). The prevalences of pulmonary hypertension (B), leg ulcers (C), and in men, priapism (D) are also related to LDH group. All statistics are significant by χ2 test for trend. The number of patients in each group (n) is indicated above each bar.
