HIV-specific CD8⁺T-cell repertoire in HIV-infected HLA-B*08⁺individuals. (A) HIV-specific CD8⁺ T-cell repertoire tested by IFN-γ ELISpot in 8 HLA-B*08⁺ HIV-infected individuals as described in “Materials and methods.” CTL magnitudes are expressed as spot-forming cells per million PBMCs (SFC/million PBMCs). (B) Pie charts display the hierarchy of IFN-γ⁺ CD8⁺ T-cell responses in the respective individual.