Physical map of the CLL candidate region. (A) Locations of polymorphic markers, shown in red. A physical map of the region was constructed using information derived from public and private databases (UCSC Genome Bioinformatics³² ; NCBI; Ensembl Genome Browser³³ ; and Celera). (B) Regions shared by the families (shown in green) with critical recombinants identifying the new minimal 3.68-Mb candidate region. (C) Location of the 13 genes within the new CLL candidate region.