Percentage of LNC numbers relative to naive control after Th1 and Th2 exposures. C57BL/6 (A) and BALB/c (B) mice were sensitized with M tuberculosis and Ascaris plus aluminum hydroxide, respectively. Mice were treated with vehicle, prednisolone, or STA-5326 orally once a day. In some studies, lymph node cells (LNCs) were harvested and counted from each mouse, and cytokine production was tested individually. Otherwise, cells were pooled within each group for cell counting and ex vivo culture. Results shown are mean ± SEM percentage of LNC numbers relative to naive control from 4 individual Th1 experiments and 6 individual Th2 experiments (*P < .05 compared with the level of the vehicle group).