RXRαΔ promotes granulopoiesis in vivo. (A) Murine BM cells transduced with RXRαΔ-IRES-GFP or empty control vector were injected into irradiated recipients. BM cells were analyzed between days 38 and 66 after BM transplantation. FACS diagrams represent gated GFP⁺ cells analyzed for Gr-1 versus CD11b. Values depict the percentages of total Gr-1^hiCD11b⁺ BM cells (top panel). Values in index charts were calculated according to the formula shown. Each dot represents data from 1 mouse (bottom diagram). Horizontal bars represent the mean values. P < .05 according to a paired 2-tailed Student t test. (B) Analysis of gated GFP⁺ cells (CD4⁺CD8⁺ thymocytes, B220⁺IgM⁺ splenocytes, and Ter119⁺ BM erythroid cells) from mice reconstituted with CTRL- or RXRαΔ-transduced BM. Numbers depict percentages of cells in each quadrant or region. Data are representative of 3 independent BMT experiments (n = 11 mice).