Partially defective superantigen-mediated proliferation in r1ΔT/r2n T cells. (A-B) Thymidine incorporation assay based on titrations of superantigen (SEB) on WT T cells, Cre− T cells (± LY), and Cre+ T cells mixed with autologous splenocytes are shown. (C) Histogram of Vβ8 TCR staining in WT (gray shading), Cre− (dotted), or Cre+ (solid black) T cells. Data are representative of 3 experiments.