TCL1 enhances Aicda expression in B cells. Isolated B220⁺ spleen B cells from WT or TCL1-tg mice were treated with LPS (10 μg/mL) plus IL-4 (50 U/mL) or anti-CD40 (1.5 μg/mL) plus IL-4 (50 U/mL), followed by 30, 35, and 40 cycles of RT-PCR to detect relative Aidca and Gapdh mRNA levels. The data are representative of 2 repeat experiments.