American Society of Hematology

Figure 2

$Figure 2. CDDO induces CD11b, CD11c, and CD16 expression and cell cycle arrest at subapoptotic doses. HL60 cells were cultured in the presence of 0.02% DMSO or different doses of CDDO for 2 days and analyzed for CD11c, HLA-DR, CD11c, CD4, CD16, and CD15 surface expression on day 5 of culture (A), or annexin V/propidium iodide positivity (B) and cell cycle phase distribution (C) using flow cytometry on day 2 of culture. Sub-G1 designates the fraction of cells that is undergoing apoptosis. The percentage of positive cells for each the designated fractions is indicated.$

CDDO induces CD11b, CD11c, and CD16 expression and cell cycle arrest at subapoptotic doses. HL60 cells were cultured in the presence of 0.02% DMSO or different doses of CDDO for 2 days and analyzed for CD11c, HLA-DR, CD11c, CD4, CD16, and CD15 surface expression on day 5 of culture (A), or annexin V/propidium iodide positivity (B) and cell cycle phase distribution (C) using flow cytometry on day 2 of culture. Sub-G1 designates the fraction of cells that is undergoing apoptosis. The percentage of positive cells for each the designated fractions is indicated.

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