Murine MSCs inhibit the response of allogeneic T cells in a dose-dependent manner. Responder BALB/c splenocytes were stimulated for 4 days with either C57Bl/6 splenocytes (A), 5 μg/mL ConA (B), or BALB/c splenocytes (C) with or without graded doses of BALB/c MSCs, C57Bl/6 MSCs, or BALB/c splenocytes. Results are expressed as the mean (± SD) cpm obtained from triplicate cultures and are representative of 3 independent experiments.