Effect of dominant-negative mutants on migration and adhesion of hematopoietic progenitor (CFU) cells. (A) SDF-1α–directed transwell migration of progenitor (CFU) cells. (B-C) Hematopoietic progenitor cell adhesion via α₄β₁ and α₅β₁, respectively, to recombinant fibronectin (see “Materials and methods” for details). In panels A to C, data are normalized to the control group and represent the mean ± SD of 3 independent experiments, *P < .01 versus control group.