(Top) Inhibition of the Wnt signaling by 5-aza-2′deoxycytidine and quercetin induces apoptosis of ALL cells. Apoptosis of ALL cells was significantly higher after treatment with quercetin (P < .05). (Bottom) Kaplan-Meier survivor function for patients with ALL. DFS curves for all the patients enrolled in this study, with an adverse impact of hypermethylated WNT inhibitors. See the complete figures in the article beginning on page .
