Proliferation of CD4⁺, but not CD8⁺ T cells from HIV⁺ patients is increased by 1-mT. (A-B) Frequency of nondividing cells, measured by CFSE dilution after 6 days of culture, in CD4⁺ T cells of PBMCs from HIV⁺ patients stimulated with PHA (A) or anti-CD3/28 (B) in presence or absence of 1-mT. (C) Individual results for 1 of 22 HIV⁺ patients and 1 of 3 HCs tested are shown for CD4⁺ T-cell proliferation in response to both PHA and anti-CD3/28 stimulation. (D-E) Frequency of nondividing cells, measured by CFSE dilution after 6 days of culture, in CD8⁺ T cells of PBMCs from HIV⁺ patients stimulated with PHA (D) or anti-CD3/28 (E) in presence or absence of 1-mT. (F) Individual results for 1 of 22 HIV⁺ patients and 1 of 3 HCs tested are shown for CD8⁺ T-cell proliferation in response to both PHA and anti-CD3/28 stimulation. For panels A-B and D-E, mean values (n = 22) ± SE are shown.