Oridonin inhibits cell growth and proliferation of t(8;21)-bearing leukemic cells. (A) Chemical structure of oridonin. (B) Effects of oridonin on Kasumi-1 cell proliferation detected by using a CCK-8 Kit. (C) Effects of oridonin on Kasumi-1 cell growth. (D) Effects of oridonin on primary leukemic cells isolated from a relapsed patient with t(8;21) leukemia. ATO indicates arsenic trioxide. Error bars represent SD of experiments.