Gross pathologic and histologic findings of leukemia in miniature swine. (A) The most consistent findings of animals with leukemias were enlarged liver and spleen, which on palpation were firm and pale in color with visible lesions, as shown by animal 15549. Image was acquired using a Kodak camera (Eastman Kodak) model Easyshare Z740 with a 45.5-mm to 55-mm lens adapter. No further image processing was done. (B) Bone marrow from these animals was predominantly populated with abnormal cells, as represented by tissue from animal 14736. Slide was viewed with an Olympus BX51 compound microscope (Olympus America) of sections stained with H&E (Hematoxylin Gill's Formulation no. 2, Fisher Diagnostics; Eosin-Y, Richard-Allan Scientific) using a lens at 400×. Image was acquired using an Olympus digital microscope camera (Olympus America) model Q-Color 3, and was processed with Adobe Photoshop CS version 8 software (Adobe Systems).