Figure 7
Other imatinib-resistant BCR-ABL mutants are also sensitive to Hsp90 inhibition. IPI-504 treatment prolonged survival of mice with CML induced by imatinib-resistant BCR-ABL-E225K (n = 10), -M351T (n = 10), or -Y253F (n = 10).
Other imatinib-resistant BCR-ABL mutants are also sensitive to Hsp90 inhibition. IPI-504 treatment prolonged survival of mice with CML induced by imatinib-resistant BCR-ABL-E225K (n = 10), -M351T (n = 10), or -Y253F (n = 10).
