Overall survival is dependent on baseline FLC values. Tertile 1 is 0.03 to 11.77 mg/dL; tertile 2 is 11.77 to 85.56 mg/dL; tertile 3 is 85.6 to 3368.5 mg/dL (n = 399). (A) Overall survival: baseline involved minus uninvolved FLC. (B) Progression-free survival: baseline involved minus uninvolved FLC. (C) Overall survival: baseline involved minus uninvolved FLC (tertile 1 vs tertile 2 + tertile 3). (D) Progression-free survival: baseline involved minus uninvolved FLC (tertile 1 vs tertile 2 + tertile 3). Data shown are results for differences between baseline involved and uninvolved FLC; however, results are similar regardless of whether absolute value or ratio of involved to uninvolved FLC is used.