Proportion of CD25⁺ Treg cells in patients with different specific subtypes of NHL correlates with disease bulk. Panels show relationships between proportions of CD25⁺ Treg cells within CD4 T cells in patients' PBMCs (n = 14) with (A) serum LDH at diagnosis and (B) clinical stages. P values were calculated using Spearman correlation test (A) and rank sum test (B). In panel A, large dots represent 3 follicular NHL/small cell lymphocytic lymphoma, an intermediate-sized dot represents a marginal zone lymphoma, and smaller dots (n = 10) represent DLBCL samples.