Rupture force spectra demonstrating the interactions of desB-fibrin and fragment D-γD364H in the absence and presence of the GHRPam and GPRPam peptides. (A) Interactions between desB-fibrin and fragment D-γD364H. (B-D) The same interactions in the presence of 2 mM, 5 mM, and 10 mM GHRPam, respectively. (E) Plot derived from panels A to D reflecting the differential inhibitory effect of GHRPam on the weak, intermediate, and strong B:b interactions (normalized by the areas of each of the 3 peaks in the absence of the inhibitor). (F) Restoration of the baseline force profile after removal of the 10 mM GHRPam. (G) The same interactions in the presence of 10 mM GPRPam, showing that the inhibitory effect of the GHRPam observed in panel D was specific.