Bone marrow therapy of established tumors. (A) Delayed tumor growth in RAG-2–deficient mice receiving bone marrow from P1CTL⁺ nu/nu mice compared to those receiving bone marrow from nu/nu mice. The growth kinetics of tumors is shown in panel A (mean ± SEM), and the survival of tumor-bearing mice (as defined by time to reach tumor size of 4000 mm³) is shown in panel B. Growth kinetics are representative of 3 independent experiments; the survival data of tumor-bearing mice are cumulative data from 2 independent experiments.