Change of mitochondrial integrity and Bcl-2 phosphorylation in eosinophils. (A) Flow cytometry analysis for rhodamine-123 in eosinophils. (B) Comparison of the loss of mitochondrial membrane integrity between CSS patients and asthma patients in various conditions (Fas ag ab indicates Fas agonistic antibody; DDR1 ag ab, DDR1 agonistic antibody; *P < .01, **P < .05, Bonferroni-Dunn test with 1-way factorial ANOVA). (C) Western blot analysis of Bcl-2 and phosphorylated Bcl-2 in eosinophils from CSS patients in the presence of DDR1 agonistic antibody. Error bars indicate standard deviation.