Figure 4
Cell-cycle distribution in human mast cells after treatment with EXEL-0862. HMC-1.1 and HMC-1.2 cells were exposed to increasing concentrations of EXEL-0862 for 24 hours. Then cells were fixed in ethanol and analyzed by flow cytometry. Accumulation of HMC-1.1 and HMC-1.2 cells in sub-G1 phase was observed with increasing doses of EXEL-0862.
