Figure 3
Figure 3. NK cell hyporesponsiveness in an IL-12p40–deficient patient. A representative experiment comparing the in vitro reactivity of NK cells from one control individual and one IL-12p40–deficient patient is shown. PBMCs were incubated for 4 hours in the presence or absence of K562 cells and assessed for CD107 and IFN-γ expression.

NK cell hyporesponsiveness in an IL-12p40–deficient patient. A representative experiment comparing the in vitro reactivity of NK cells from one control individual and one IL-12p40–deficient patient is shown. PBMCs were incubated for 4 hours in the presence or absence of K562 cells and assessed for CD107 and IFN-γ expression.

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