Relative expression of IGKV and IGLV genes in subgroups of CLL samples. Values are expressed as a percentage of samples found to use each IGKV or IGLV gene. (A) Comparison of IGKV used by 182 CLL samples in this study that express κ light chains (51p1 CLL), with 179 samples reported by Stamatopoulos et al²³  (κ CLL), and the 89 samples in the latter cohort that express unmutated Ig (κ CLL NM). (B) Comparison of IGLV used by 76 CLL samples in this study that express λ light chains (51p1 CLL), with 97 reported by Stamatopoulos et al²³  (λ CLL), and the 53 samples in the cohort that express unmutated Ig (λ CLL NM). Other IGKV and Other IGLV represent the IGKV and IGLV genes, respectively, that are present in less than 3% of the light chains within each of the 3 groups of CLL samples.