Submicroscopic del(9)(q34.11q34.13) in T-ALL. (A) Chromosome 9 ideogram and corresponding oligo array-CGH plots of test DNA–control DNA ratios (blue tracing) versus the dye-swap experiment (red tracing) for patient no. 126. Detailed analyses of the centromeric and telomeric breakpoints show involvement of SET and NUP214. (B) Similar array-CGH plot for patient no. 120. Centromeric and telomeric breakpoints show involvement of SET and ABL1. (C) Overview of oligoarray-CGH results in the potential breakpoint regions for 3 patients with T-ALL with del(9)(q34.11q34.13). The 60-mer oligonucleotide probes present on the array-CGH slide and located in the telomeric and centromeric breakpoint regions, as well as the specific genes located in this region with their transcription direction, are shown. Abbreviations: N; normal, L; loss. Dual-color FISH analysis of patient no. 125 (D) and no. 120 (E) using the LSI BCR-ABL ES translocation probe.