Sorafenib, but not sunitinib, induces apoptosis of DCs. DCs generated by culturing adherent monocytes in the presence of GM-CSF and IL-4 for 7 days were incubated for 48 hours with sorafenib (A) or sunitinib (B). Cells were harvested, washed, stained according to Nicoletti et al,²⁵  and then analyzed by flow cytometry (*P < .05, **P < .001).