Kaplan-Meier curve for the occurrence of “AIDS-defining clinical conditions” during follow-up. Five “AIDS-defining” opportunistic infections occurred during the follow-up of 36 patients with ICL within the first 24 months of follow-up. Bottom line represents the number of ICL patients still on follow-up at 12-month intervals. Vertical lines represent the time at which patients were censored (end of follow-up or occurrence of an “AIDS-defining clinical condition”). MAC indicates M avium complex; EBVLPD, Epstein-Barr virus lymphoproliferative disease; PCP, P jirovecii pneumonia; PML, progressive multifocal leucoencephalopathy.