Wnt3a has no effect on subcutaneous MM growth in SCID mice. SCID mice were subcutaneously injected with H929/W3A or H929/EV cells. (A) Circulating human Ig levels were similarly increased in hosts engrafted with EV and W3a cells. (B) Subcutaneous tumor volume. Error bars represent SEM. (C) X-ray radiographs showing similar tumor size (white arrows) in hosts with H929/EV and H929/W3A cells.