Analysis of MK ploidy status of GATA-1-surv mice. Representative MK ploidy profiles of wild-type (wt) and GATA-1-surv mice. Average MK ploidy displayed no significant change between wild-type and transgenic mice (n = 5 mice per group). Differences in ploidy profiles between GATA-1-surv MKs and PF4-surv mice (Table 2) could be due to the different mouse strains (FVB and CD-1; see Document S1).