Figure 1
The relationship between the percentage release of C-serotonin from platelets obtained from healthy individuals (ordinate) and the final concentration of heparin (abscissa). Each series of points is the result obtained with serum from a different patient with definite heparin-induced thrombocytopenia, The lines numbered 1 to 4 represent 4 different serum samples not from patients with heparin-induced thrombocytopenia. These samples induced release at 0.1 and 100 U/mL of heparin. Numbers 1 and 2 are sera from 2 patients with immune thrombocytopenic purpura. Number 3 is the serum from a hospitalized control, and number 4 is heat-aggregated IgG. Adapted from Sheridan et al31 with permission.
