AML1-D171N induced a biphenotypic leukemia in concert with Evi1 in the BMT model. The dot plots show Ly5.1, Gr-1, CD11b, B220, CD3, CD41, c-kit, Sca-1, CD34, or Ter119 labeled with a corresponding PE-conjugated mAb versus expression of GFP. BM cells of morbid mice/D171N with high expression of Evi1 (mouse IDs 6, 20, and 26) and those of morbid mice/D171N + Evi1 (mouse IDs 302 and 305) displayed a similar pattern of surface markers, CD11b+ and B220+.