Histone H3K9me3 and H3K27me3 modifications at lymphoid genes in CD34+CD38lo cells. ChIP analyses of multipotent CD34+CD38lo (▭), erythroid GpA+ (), and B-committed CD19+ () cells with antibodies to H3K9me3 and H3K27me3. Histone modifications at B-lymphoid (B), T-lymphoid (T), erythroid (E), and nonhematopoietic (N) genes were normalized to the nonhematopoietic THP gene (set at 1). Results are means and standard deviations of 2 to 5 independent ChIP experiments analyzed in triplicate. ND indicates not determined.