Prosurvival pathway modules are differentially up-regulated in resistant ALL 8 hours after IR. At 8 hours after 5 Gy IR, 11 representative samples of apoptosis-resistant ALL show differential coordinate up-regulation of genes involved in prosurvival pathways compared with the apoptosis-sensitive tumors. Each column represents a different patient sample, and each row represents a pathway consisting of a number of genes given in parentheses. Color changes within a row indicate expression levels relative to the average of the same population. Red indicates up-regulation; green, down-regulation.