131I-L19SIP uptake in lymphoma lesions in a patient (NHL1) with SLL NHL. (A) 18F-FDG PET scans demonstrate intense glucose metabolism in multiple enlarged lymph nodes, particularly in the left latero-cervical region. Coronal images are shown in the left panels and transaxial images of the cervical regions are displayed in the right panels. (B) The same patient received an intravenous infusion of 185 MBq and, subsequently, 5.55 GBq 131I-L19SIP. Transaxial, coronal, and sagittal SPECT-CT images of the cervical regions (first, second, and third rows, respectively) were acquired 8 days after the dose of 5.55 GBq. Left column shows scintigraphic images; central column, CT images; and right column, CT-scintigraphy fused images.