¹⁸F-FDG PET scans and ¹³¹I-L19SIP SPECT-CT images from an advanced Hodgkin lymphoma patient (HL1).¹⁸F-FDG PET scans show intense glucose metabolism in multiple enlarged mediastinal lymph nodes, intrapulmonary lesions (leftmost column, first 4 images; intrapulmonary lesion marked), as well as in lumboaortic lymph nodes (leftmost image in lowest row). The same patient received intravenous injections of 185 MBq and, subsequently, 5.55 GBq ¹³¹I-L19-SIP. SPECT-CT coronal (top right panel) and transaxial images of the thorax (rows 2-4) as well as the upper abdomen (lowest row) are shown, demonstrating selective uptake of ¹³¹I-L19SIP into the ¹⁸F-FDG–labeled lymphomatous lesions.