Interrelationships between genes involved in the DNA damage-response, immune regulation, and cell-signaling pathways for SNPs associated with PFS in CLL. Interactions were established using Pathway Assist software and are color-coded: blue indicates expression; gray, regulation; and red, protein binding. Supporting publications are indicated with the corresponding National Center for Biotechnology Information (NCBI) Entrez PubMed ID in parentheses. 1, binding (14988562); 2, binding (11375975); 3, binding (15525513); 4, binding (11799067); 5, binding (12808131); 6, regulation (14744757); 7, binding (11279041); 8, binding (15735755); 9, regulation (10490955); 10, promoter binding (10942771); 11, promoter binding (1480019); 12, promoter binding (8018731); 13, binding (7498414); 14, regulation (10487844); and 15, regulation (11595644).