Granzyme B mRNA level is affected by sHSP70. Granzyme B mRNA levels in CD3⁺ T cells (A) or independently stimulated CD4⁺ (B) or CD8⁺ T cells (C) were assessed by real-time PCR after 6 hours of stimulation with the K562 target cells. Results of 8 independent experiments are expressed as mean plus or minus SD. Comparison between groups was performed using t tests. Statistically significant differences are indicated with asterisks (*P < .05 or **P < .01).