TG101209, a Jak-2 inhibitor, reduced splenomegaly in thalassemic mice. Representative FACS analysis of 6-week-old th3/+ mice injected for 10 days with TG101209 or placebo, as indicated. The corresponding spleens and the Hb levels are shown. Numbers on plots are percentages of total cells in the respective gates. The weight of the spleens of these and other animals treated with TG101209 or placebo is indicated in Figure S5.