Cumulative incidence of secondary therapy among patients with acute GVHD initially given either low-dose glucocorticoids (prednisone-equivalent dose of 1 mg/kg per day) or standard-dose glucocorticoids (prednisone-equivalent dose of 2 mg/kg per day). (Left panel) Nonglucocorticoid secondary therapy. (Right panel) Increased glucocorticoid dose or nonglucocorticoid secondary therapy.