Kinetics of NK-cell expansion and cytokine serum-levels in relation to viral load, and phenotype of the expanded NK cells. (A) Number of CMV-DNA copies (■-■) and number of NK cells (◇-◇). The number of NK in the last sample (day 50) is at the upper limit of that in normal age-matched controls. → indicates the first day of oral valganciclovir given to maintain CMV suppression. (B,C) Serum cytokine-levels during viremia (, day 9 in panel A) and in a late CMV-DNA free sample (, day 43 in panel A). □ depicts the mean value plus or minus SD in 10 healthy controls. (D) FACS analysis of the respective marker with gates on CD3-CD56⁺ lymphocytes.