Heat map of the FLT3-TKD–associated gene signature. Expression values of the 333 probe sets in the signature are represented by color, with blue indicating expression below and red expression above the median value for the given probe set. For display purposes, the expression values of the probe sets were centered so that each probe set has the same median expression value. Rows represent probe sets (Table S2, identification of probe sets) and columns represent patients. Patients are grouped by FLT3-TKD (+) and FLT3-WT (−) status. NPM1 status is indicated as mutation positive (M) or wild-type (WT).