CXCL12-induced (500 ng/mL) accumulation of PIP3 at the plasma membrane of CD4⁺ T-cell blasts is dependent on p110γ but not p110δ. (A) Representative images showing the translocation of the AktPH-GFP probe to the plasma membrane. (B) Graphical representation of the percentage of total fluorescence at the plasma membrane as function of time. Data are representative of 2 independent experiments (WT, n = 6; p110δ^D910A/D910A, n = 4; p110γ^−/−, n = 5).