SYK and ZAP-70 changes upon stimulus. SYK (A) and ZAP-70 (B) expression upon 24 hours of BCR stimulation between unstimulated (US) and stimulated (S) samples in CLL unmutated (UM) and mutated (M) cases. Gene expression values are expressed by ΔCT values: low ΔCT values correspond to high gene expression levels.