Subject heterogeneity in the expression of signaling components in CD4 and CD8 T-cell subsets. Subject heterogeneity as expressed by CV of the 15 signaling components (n = 15) under study in 8 to 13 cumulated subjects in CD4 (A) and CD8 (B) T-cell subsets. Box plots were automatically generated using GraphPad, the box represents values between 25th and 75th percentile with a line at the median (50th percentile). The whiskers extend above and below the box to show the highest and the lowest values. Shown are signaling components with highest subject heterogeneity in CM or EM cells.