UA favors an IL-5–based Th2 immune response. (A,B) The cytokine concentrations of cell culture supernatants from purified antigen-stimulated DO11.10 CD4 T cells stimulated by DCs stimulated with either control media (control) or 10 μg/mL UA (UA) and ovalbumin antigen (OVAL). Each represents the mean (± SEM) cytokine concentration from duplicate wells. Experiment was reproduced twice with similar results. (C,D) Cytokine concentrations of cell culture supernatants from purified CD11C⁺ splenic dendritic cells stimulated with UA (UA) or media alone (CONT). Each represents the mean (± SEM) cytokine concentration from duplicate wells. Experiment was reproduced twice with similar results.