Figure 1
Analysis of EBV genome load in healthy control donors and patients with EBV-associated disease. (A) Results of quantitative PCR analysis to determine the EBV load in PBMC samples isolated from control donors, from XLP patients or from an EBV-AHS (VAHS) patient. Data are reported as EBV genome copies per 106 PBMCs, with the median value for each group denoted by the horizontal bar. (B) Results of quantitative PCR analysis to determine the EBV load in CD19+ B-cell (
) and CD19− non–B-cell (
) fractions isolated from XLP and VAHS PBMC samples. Data (mean and SD of 3 replicates) are reported as EBV genome copies per 106 cells.
