Kaplan-Meier survival analysis of patients with diffuse large B-cell lymphoma stratified by TP53 mutation status. (A) Distribution pattern of TP53 mutations in the central core domain model designed from published crystal structure⁴¹  (red indicates patients with poor survival; green, patients with survival similar to WT group; blue, survival data unavailable). (B) Overall survival of patients with TP53 mutations versus those with WT-TP53. (C) Overall survival of patients with DNA-binding domain mutations versus those with WT-TP53. (D) Overall survival of patients with non–DNA-binding domain mutations versus those with WT-TP53.