Cdc42 confers immunoresistance of cancer in vitro. (A) The 5-hour ⁵¹Cr release assay of cA2K^b-Cdc42 (● ○) or cA2K^b-control MEFs (■ □ coincubated with allo-A2 CTLs (● ■) or A2 Flu control CTLs (○ □). Mean values plus or minus SD of 3 independent experiments are shown. (B) Clonogenic survival of cA2K^b-Cdc42 and cA2K^b-control MEFs coincubated with allo-A2 CTLs at the indicated E/T ratios (representative photograph of at least 3 independent experiments). (C) Clonogenic survival of HCT116-Cdc42 and HCT116-control human colorectal cancer cells coincubated with allo-A2 CTLs (representative photograph of 3 independent experiments).