BIRCS expression contributes to cell viability. BIRC5 RNA levels (A) and cell viability (B) for ATL15 PBLs electroporated with shRNA control or BIRC5 vectors (Superarray Bioscience). The control values were set to 1. For these studies, cells directly from the patient were cultured in media containing 20% fetal bovine serum, 2 mM l-glutamine, and 50 U IL-2.